DDX41: A key nuclear participant in sustaining genomic stability

The gene DDX41 encodes the nuclear enzyme, DEAD-box-type RNA helicase. Mutation of DDX41 results in hematopoietic cancers. Nonetheless, the mechanism underlying this malignancy growth is unclear. To this finish, researchers characterised the useful significance of DDX41 in nice element. Their findings reveal that DDX41 serves essential features in transcriptional processes, RNA splicing, and general genomic integrity upkeep. The findings might maintain significance in treating hematopoietic malignancies.