Pakistan set simply 142 for victory, a totally altered England XI after a coronavirus outbreak inside the initially chosen squad, completed on 142-1 with greater than 28 overs remaining.
Dawid Malan was 68 not out and Zak Crawley 58 not out, the pair sharing an unbroken stand of 120,
Earlier, quick bowler Saqib Mahmood took an ODI greatest 4-42 as Pakistan have been dismissed for 141 with greater than 14 overs of their innings left.
The 24-year-old Lancashire quick bowler, in simply his fifth match at this degree and first in almost a 12 months, took two wickets in three balls within the first to depart Pakistan reeling after England stand-in captain Ben Stokes gained the toss.
Solely opening batsman Fakhar Zaman, with 47, and Shadab Khan (30) provided a lot resistance within the first of this three-match sequence.
And when World Cup-winner Stokes caught Shaheen Shah Afridi to finish the innings, Pakistan had greater than 14 overs left to bat.
Such was England’s command that Stokes, regardless of being essentially the most skilled member of the assault, bowled simply the one over.
England have been fielding a wholly new XI, together with 5 debutants, after a coronavirus outbreak inside their current squad throughout a latest 2-0 sequence win at house to Sri Lanka meant all 16 gamers initially chosen to play in opposition to Pakistan have been compelled to self-isolate.
As well as, England have been additionally lacking quick bowlers Jofra Archer and Olly Stone and wicketkeeper-batsman Jos Buttler via damage.
However they nonetheless made a sensational begin when Mahmood had Imam-ul-Haq lbw with the primary ball of the match after a evaluate ordered by Stokes confirmed the supply had pitched in line.
Two balls later, Mahmood had a prize wicket when Pakistan captain Babar Azam — the world’s top-ranked ODI batsman — additionally fell for a duck after edging to Zak Crawley at second slip, with Pakistan but to attain a run.
Mohammad Rizwan had made 13 when he edged an outstanding, late-moving, supply from Lewis Gregory to debutant wicketkeeper John Simpson.
And when Mahmood had Pakistan debutant Saud Shakeel lbw for 5, the vacationers have been 26-4 from seven overs
However Zaman, on a floor the place he had made a fifty in Pakistan’s 2017 Champions Trophy semi-final win over England, counter-attacked.
The left-handed opener hit a number of superb boundaries, a 4 via the covers off Gregory adopted by a pull off Craig Overton and an outstanding drive straight down the bottom off debutant quick bowler Brydon Carse.
New batsman Sohaib Maqsood, taking part in in his first ODI for 5 years, flat-batted Carse over extra-cover for six.
However a promising stand of 53 resulted in farcical style when non-striker Maqsood, lured down the pitch by the advancing Zaman’s name for a single, was undone when his accomplice out of the blue stopped, with James Vince operating him out for 19.
Pakistan, restricted to intra-squad moderately than tour matches, badly wanted the in-touch Zaman to maintain going.
Nonetheless, his 67-ball innings, together with six fours, ended tamely when he miscued a reduce off leg-spinner Matt Parkinson and gave a mild catch to backward level.
And when Mahmood had Faheem Ashraf caught behind, Pakistan have been 101-7.
Shadab, dropped on six, checked England’s progress earlier than he holed out off Craig Overton.