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Researchers determine therapeutic targets to beat radioresistance of mind most cancers cells

Glioblastoma (GBM) is a WHO grade IV mind tumor with dismal prognosis. Though post-surgical radiation chemotherapy mixed with temozolomide is the usual line of therapy, GBM cells surviving radiotherapy contribute to tumor development and recurrence much more aggressively. Researchers have now unveiled the mechanism of radioresistance in GBM cells, figuring out therapeutic targets to beat radioresistance. Furthermore, the group has found a scientific drug that sensitizes GBM cells to radiotherapy and will change temozolomide.