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Pungent, bitter, and painful: A novel insect repellent assaults a number of sensory pathways

Researchers discovered {that a} Transient Receptor Potential (TRP) A1 stimulant, 2-methylthiazoline (2MT), act as a potent insect repellent in Drosophila. 2MT induces aversive behaviors through olfactory, gustatory, and nociceptive sensory pathways. 2MT acts on TRPA1 by particular cysteine residues which might be conserved throughout many insect pest species.