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Examine uncovers mechanisms needed for SARS-CoV-2 an infection in macrophages

Researchers have recognized a receptor, CD169 (additionally known as Siglec1), that’s solely expressed on macrophages and contributes to the hyper-inflammatory response of macrophages upon an infection with SARS-CoV-2. These findings, they imagine, might present a proof of how SARS-CoV-2 an infection of macrophages in lungs of COVID-19 sufferers promote inflammatory responses.